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fosphenytoin will lessen the level or effect of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.apalutamide will lower the extent or effect of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Stay clear of or Use Alternate Drug. Coadministration of apalutamide, a robust CYP2C19 inducer, with medicati